A new treatment aimed at clearing abnormal clumps of protein called tau tangles from the brain in Alzheimer’s disease is entering an early-stage clinical trial in the UK. The treatment, known as ACI-35, is being tested in a clinical trial run by a Swiss company called AC Immune. The trial will be led by Prof Roy Jones, a consultant geriatrician based in Bath, and run across sites in Bath, Liverpool and Finland
A Danish study has revealed an association between alcohol consumption and mortality in people with Alzheimer’s disease. The research was published in the journal BMJ Open on 10 December 2015.
Alzheimer’s Research UK has appointed three Chief Scientific Officers to drive its £30million Drug Discovery Alliance. The Alliance, which unites three Drug Discovery Institutes at the University of Cambridge, the University of Oxford and University College London, is a unique drug discovery venture in dementia research.
Newly-released follow-up analysis from a 2012 clinical trial led by a UK-based research team suggests that continuing treatment of the commonly-prescribed dementia drug donepezil into the later stages of Alzheimer’s could reduce a person’s likelihood of moving into a nursing home.
Cambridge dementia scientists are set to benefit from nearly three quarters of a million pounds of new funding from Alzheimer’s Research UK, the UK’s leading dementia research charity.
Researchers in the United States have looked at the impact of Vitamin D levels on memory and thinking difficulties. The new research was published on 14 September 2015 in the JournalJAMA Neurology.
A study published today by London researchers has revealed evidence that the hallmark Alzheimer’s protein, amyloid, may have been passed to a small number of people through human-derived growth hormone treatments given before the mid-1980s. The research suggests that amyloid, which builds up in the brain in Alzheimer’s, could be transmitted through contaminated brain tissue extracts in a similar way to the prion protein responsible for Creutzfeldt-Jakob disease (CJD). The findings are published on 9 September in the journal Nature and funded by the NIHR UCL/UCLH Biomedical Research Unit and the Medical Research Council
Researchers in the United States have conducted two clinical trials to assess the benefit of nutritional supplements and exercise on memory and thinking skills. The studies were published in the Journal of the American Medical Association on 25 August 2015.
A number of studies presented at the Alzheimer’s Association International Conference, showed that regular supervised exercise sessions could help to improve symptoms in people with memory problems and dementia
Results of a phase 3 trial of Alzheimer’s drug solanezumab are to be presented today (22 July) at the Alzheimer’s Association International Conference 2015.