As the UK today hosts the first G8 summit on dementia research, a new £3 million Dementia Consortium bringing together research experts from the charitable, academic and private sectors has launched to expedite development of new drugs for dementia.
Category Archives: The Clinic
Evidence review shows exercise may benefit people with dementia
A systematic review of trials into exercise has shown it may help improve cognition for people with dementia and their ability to perform day to day activities. The review is published by The Cochrane Collaboration.
Review suggests statin use not linked to cognitive decline
A systematic review of current evidence, completed by a research team in the US, has found that there is not enough evidence to link statin use to cognitive decline or an increased risk of Alzheimer’s.
Drug Discovery Institute announced by Alzheimer’s Research UK
With the G8 Dementia Summit one month away, the UK’s leading dementia research charity Alzheimer’s Research UK has announced a first of its kind in Europe with the launch of a Drug Discovery Institute to develop new treatments for dementia.
Over 90 percent of dementia cases in China are undetected
An international team of researchers co-funded by Alzheimer’s Research UK has found that over 90 percent of dementia cases in China go undetected, with a high level of undiagnosed dementia in rural areas.
Progress in Alzheimer’s drug trial targeting inflammation
A team of researchers will present findings at the Alzheimer’s Association International Conference 2013 from a clinical trial testing an experimental drug, called CHF5074, in people with early memory problems.
Potential Alzheimer’s treatment to begin phase 3 trials
It was announced today that phase III clinical trials of a potential Alzheimer’s treatment, called LMTX, have begun in the UK. About 16 centres across the UK are expected to participate in the trials, which will involve people with mild to moderate stage Alzheimer’s disease.
B vitamins slow brain changes in a subgroup of older people
Dementia researchers at the University of Oxford have released additional data from a clinical trial carried out in 2010, which suggested that high dose B vitamins could halve brain shrinkage in older people with memory problems. The new findings delve deeper into the data, linking B vitamin supplementation to slower rates of shrinkage specifically in areas of the brain affected in Alzheimer’s disease in people with high levels of homocysteine. The results are part-funded by Alzheimer’s Research UK and published online in the journal Proceedings of the National Academy of Sciences, USA.
Evidence suggests mental exercise may prevent cognitive decline
A review of existing evidence has concluded that mental exercise may help prevent cognitive decline in older people, but that evidence for other potential preventions is limited. The review, which was carried out by doctors in Canada, is published on 15 April in the Canadian Medical Association Journal.
Potential new Alzheimer’s drug passes phase 2 trials
American Academy of Neurology Conference: Safety and efficacy of ORM-12741 on cognitive and behavioural symptoms in patients with Alzheimer’s disease: A randomized, double-blind, placebo-controlled, parallel group, multicenter, proof-of-concept 12-week study.